NORMAL RATES OF FORGETTING OF VERBAL AND NONVERBAL MATERIAL IN ALZHEIMERS-DISEASE
NORMAL RATES OF FORGETTING OF VERBAL AND NONVERBAL MATERIAL IN ALZHEIMERS-DISEASE
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DOI：
10.1016/s0010-9452(87)80019-9
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发表时间：
1987-03-01
期刊：
影响因子：
3.6
通讯作者：
MCGONIGLEGIBSON, KL
中科院分区：
文献类型：
--
作者：
BECKER, JT;BOLLER, F;MCGONIGLEGIBSON, KL
最近的研究表明，颞叶结构受损的患者，如阿尔茨海默病（AD）患者，以异常快的速度丢失记忆中的信息。相反，其他研究的数据表明，AD的遗忘率是正常的。在本研究中，62例轻度至中度AD患者和64名老年对照者进行了测试，他们的即时和延迟回忆的一个简短的口头通道和修改后的雷伊复杂的数字。结果表明，虽然AD患者回忆起的比对照组少，但他们在30分钟的保留时间内并没有以更快的速度忘记，这支持了这些记忆受损患者没有异常遗忘率的发现。这些数据还表明，不良的初始编码的刺激可能是AD患者的回忆受损的原因。
Recent work has suggested that patients with damage to temporal lobe structures, such as patients with Alzheimer''s Disease (AD), lose information form memory at an abnormally rapid rate. In contrast, data from other studies suggest that the rate of forgetting in AD is normal. In the present study, 62 patients with mild to moderate AD and 64 elderly controls were tested for their immediate and delayed recall of a short verbal passage and a modified Rey complex figure. The results suggest that although AD patients recalled less than controls, they did not forget at a faster rate during the 30 minute retention interval, supporting the finding that these memory impaired patients do not have an abnormal rate of forgetting. The data also suggest that poor initial encoding of the stimuli may be the cause of the AD patients'' impaired recall.