Norovirus Outbreak Surveillance, China, 2016-2018
Norovirus Outbreak Surveillance, China, 2016-2018
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DOI：
10.3201/eid2603.191183
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发表时间：
2020-03-01
影响因子：
11.8
通讯作者：
Duan, Zhaojun
中科院分区：
文献类型：
--
作者：
Jin, Miao;Wu, Shuyu;Duan, Zhaojun
CaliciNet China是由中国疾病预防控制中心协调的省、县、市实验室网络，于2016年10月启动，旨在监测中国诺如病毒疫情的流行病学和基因型分布。在2016年10月至2018年9月期间，共报告了556起诺如病毒疫情，并对470起（84.5%）疫情的阳性粪便样本进行了基因分型。这些暴发大多数与人际传播有关（95.1%），发生在儿童保育中心或学校（78.2%），并在每年11月至3月期间报告（63.5%）。在为期2年的研究期间，81.2%的诺如病毒暴发被分型为GII.2[P16]。在中国，大多数诺如病毒暴发是由儿童保育中心或学校报告的; GII.2[P16]是主要的基因型。CaliciNet中国的持续监测将提供有关不断变化的诺如病毒基因型分布和疫情特征的信息，这些信息对于制定有效的干预措施（包括疫苗）至关重要。
CaliciNet China, a network of provincial, county, and city laboratories coordinated by the Chinese Centers for Disease Control and Prevention, was launched in October 2016 to monitor the epidemiology and genotype distribution of norovirus outbreaks in China. During October 2016-September 2018, a total of 556 norovirus outbreaks were reported, and positive fecal samples from 470 (84.5%) outbreaks were genotyped. Most of these outbreaks were associated with person-to-person transmission (95.1%), occurred in childcare centers or schools (78.2%), and were reported during November-March of each year (63.5%). During the 2-year study period, 81.2% of all norovirus outbreaks were typed as GII.2[P16]. In China, most norovirus outbreaks are reported by childcare centers or schools; GII.2[P16] is the predominant genotype. Ongoing surveillance by CaliciNet China will provide information about the evolving norovirus genotype distribution and outbreak characteristics important for the development of effective interventions, including vaccines.