The direct health services costs of providing assisted reproduction services in overweight or obese women: a retrospective cross-sectional analysis
The direct health services costs of providing assisted reproduction services in overweight or obese women: a retrospective cross-sectional analysis
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DOI：
10.1093/humrep/den424
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发表时间：
2009-03-01
影响因子：
6.1
通讯作者：
Bhattacharya, Siladitya
中科院分区：
文献类型：
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作者：
Maheshwari, Abha;Scotland, Graham;Bhattacharya, Siladitya
超重和肥胖的患病率正在上升。因此，接受辅助生殖治疗的女性中超重或肥胖的比例可能更高。在一项使用英国试管受精室和三级医疗机构妇产医院常规收集的数据进行的回溯性横断面分析中，评估了所有体重类别的直接成本。在1997至2006年间接受第一个体外受精周期的1756名妇女中，43人(2.4%)体重不足；988人(56.3%)BMI正常；491人(28.0%)超重；148人(8.4%)肥胖(I级)，86人(4.9%)肥胖(II级)。体重不足组每例活产的平均成本(95%CI)为18/747(13 864~27 361)，体重指数正常组为16/497(15 374~17 817)，超重组为18/575(16 648~21 081)，肥胖组为18/805(15 397~23 554)，肥胖组为20/282(15 288~28 424)，与体重指数正常组、超重组和肥胖组比较差异无统计学意义。然而，由于产科并发症的增加，即使在超重或肥胖(I类)的妇女中，仍应建议在开始试管受精之前减肥。
Prevalence of overweight and obesity is rising. Hence, it is likely that a higher proportion of women undergoing assisted reproduction treatment are overweight or obese.In a retrospective cross-sectional analysis using routinely collected data of an IVF Unit and maternity hospital in a tertiary care setting in the UK, direct costs were assessed for all weight classes. Costs for underweight, overweight and obese were compared with those for women with normal body mass index (BMI).Of 1756 women, who underwent their first cycle of IVF between 1997 and 2006, 43 (2.4%) were underweight; 988 (56.3%) had normal BMI; 491 (28.0%) were overweight; 148 (8.4%) were obese (class I) and 86 (4.9%) were obese (class II). The mean (95% CI) cost of each live birth resulting from IVF was 18 pound 747 (13 864-27 361) in underweight group; 16 pound 497 (15 374-17 817) in women with normal BMI; 18 pound 575 (16 648-21 081) in overweight women; 18 pound 805 (15 397-23 554) in obese class I; 20 pound 282 (15 288-28 424) in obese class II or over.The cost of a live birth resulting from IVF is not different in underweight, overweight and obese class I when compared with women with normal BMI. However, due to increased obstetric complications weight loss should still be recommended prior to commencing IVF even in overweight or obese (class I) women.