What Do Repetitive and Stereotyped Movements Mean for Infant Siblings of Children with Autism Spectrum Disorders?
What Do Repetitive and Stereotyped Movements Mean for Infant Siblings of Children with Autism Spectrum Disorders?
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DOI：
10.1007/s10803-012-1681-y
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发表时间：
2013-06-01
影响因子：
3.9
通讯作者：
Stone, Wendy L.
中科院分区：
文献类型：
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作者：
Damiano, Cara R.;Nahmias, Allison;Stone, Wendy L.
婴儿期的重复和刻板动作（RSM）与自闭症谱系障碍（ASD）的后期诊断有关，但这种关系尚未在高危人群中得到充分探讨。本研究调查了涉及物体和身体使用的RSM如何与ASD儿童（Sibs-ASD）和典型发育儿童（Sibs-TD）的婴儿兄弟姐妹的诊断结果相关。在平均15个月时测量不同类型RSM的发生率和数量，并在大约18个月后进行随访诊断评估。虽然同胞ASD相对于同胞TD显示出更高的RSM率，但根据同胞ASD的诊断结果，比率没有差异。然而，初步证据表明，RSM类型的定性差异值得进一步研究作为早期诊断标志物。
Repetitive and stereotyped movements (RSMs) in infancy are associated with later diagnoses of autism spectrum disorder (ASD), yet this relationship has not been fully explored in high-risk populations. The current study investigated how RSMs involving object and body use are related to diagnostic outcomes in infant siblings of children with ASD (Sibs-ASD) and typically developing children (Sibs-TD). The rate and number of different types of RSMs were measured at an average of 15 months with follow-up diagnostic evaluations approximately 18 months later. While Sibs-ASD displayed higher rates of RSMs relative to Sibs-TD, rates did not differ according to diagnostic outcome in Sibs-ASD. However preliminary evidence suggests that qualitative differences in RSM type warrant further investigation as early diagnostic markers.