Hepatic resection in 120 patients with hepatocellular carcinoma.
Hepatic resection in 120 patients with hepatocellular carcinoma.
复制标题
120例肝细胞癌患者的肝切除术。
作者：
Miin;T. Hwang;L. Jeng;Y. Jan;Chia‐Siu Wang;Fong
从1977年到1987年的11年间，对120名肝细胞癌（HCC）患者进行了肝切除术。 25 例的 HCC 直径小于 5 厘米。其中男97例，女23例，平均年龄51.5岁。其中，45.8%患有肝硬化，80.8%乙型肝炎表面抗原阳性。 14 例肝癌破裂者接受了肝切除术以控制腹内出血。术后1个月内的手术死亡率为4.1%。术后并发胸腔积液5.8%，膈下脓肿2.5%，术后出血1.6%，肝功能衰竭1.6%，胆漏0.8%。该系列的总体五年生存率为 25.9%，而过去五年的生存率更好（1977 年至 1982 年间接受治疗的患者为 42.3% 对比 11.9%）。累积生存率与肿瘤破裂或肝硬化无关。肿瘤较小（直径小于5厘米）或肿瘤无血管侵犯的患者组生存率较好。
During the 11-year period from 1977 through 1987, hepatic resections were carried out in 120 patients with hepatocellular carcinoma (HCC). Twenty-five had HCCs smaller than 5 cm in diameter. There were 97 male and 23 female patients, with an average age of 51.5 years. Among them, 45.8% had liver cirrhosis and 80.8% were positive for hepatitis B surface antigen. Fourteen with ruptured HCCs underwent hepatic resection to control the intra-abdominal hemorrhage. Operative mortality within one month after surgery was 4.1%. The postoperative course was complicated by pleural effusion in 5.8%, subphrenic abscess in 2.5%, postoperative bleeding in 1.6%, hepatic failure in 1.6%, and bile leakage in 0.8% of the patients. The overall five-year survival rate in this series was 25.9%, while survival for the last five years was better (42.3% vs 11.9% for patients treated between 1977 and 1982). The cumulative survival rate had no relation to tumor rupture or liver cirrhosis. The group of patients with smaller tumors (diameter, less than 5 cm) or without vascular invasion by tumor had better survival.