Individual-Specific Analysis for Psychoradiology.
Individual-Specific Analysis for Psychoradiology.
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DOI：
10.1016/j.nic.2019.09.003
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发表时间：
2020-02
影响因子：
2.3
通讯作者：
Hesheng Liu;William J Liu;Danhong Wang;L. Dahmani
中科院分区：
文献类型：
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作者：
Hesheng Liu;William J Liu;Danhong Wang;L. Dahmani
许多放射学方法的进步，如功能性磁共振成像，提供了关于精神障碍机制的见解。事实上，这些神经影像学方法为大量关于精神障碍潜在神经基质的文献做出了贡献，特别是精神放射学作为神经放射学新兴亚专业的发展，开始显示出在指导精神病患者的诊断决策和治疗计划方面发挥作用的潜力（Huang et al，2019; Port，2018; Sun et al，2018）。然而，大多数精神疾病的神经机制仍然非常模糊。目前，围绕精神疾病临床诊断的理想标准以及当前指南是否适用于实际应用存在争议（Cuthbert & Insel，2013; Frances，2013）。精神病学家和研究人员是否从基于症状的严格分类方法过渡到也考虑来自神经影像数据的维度，将对精神病学未来的临床实践产生重大影响。这一进展将需要进一步发展神经成像技术，以准确表征个体受试者的大脑。以下旨在解决个人特异性分析如何影响精神病学研究，以及它如何在未来被用作心理放射学的一个组成部分。
Advancements in numerous radiological modalities such as functional magnetic resonance imaging have provided insight regarding the mechanisms of mental disorders. Indeed, these neuroimaging methods have contributed to a robust body of literature concerning potential neural substrates of mental disorders, and in particular, the development of Psychoradiology as an emerging subspecialty of neuroradiology, began to show potential to play role in guiding diagnostic decision and therapeutic planning in psychiatric patients (Huang et al, 2019; Port, 2018; Sun et al, 2018). However, the neural mechanisms for most psychiatric disorders remain very obscure. Currently, there is contention surrounding the ideal criteria for the clinical diagnosis of psychiatric disorders and whether the current guidelines are suitable for practical use (Cuthbert & Insel, 2013; Frances, 2013). Whether psychiatrists and researchers transition from a strictly categorical approach based on symptoms to one that also considers dimensions derived from neuroimaging data will hypothetically have large implications on future clinical practice in psychiatry. This progression will require further developments in neuroimaging techniques to enable accurate characterization of the individual subject’s brain. The following seeks to address how individual-specific analysis impacts psychiatric research and how it may be used as a component of psychoradiology in the future.