Physical properties of biological entities: an introduction to the ontology of physics for biology.
Physical properties of biological entities: an introduction to the ontology of physics for biology.
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DOI：
10.1371/journal.pone.0028708
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发表时间：
2011
期刊：
影响因子：
3.7
通讯作者：
Gennari JH
中科院分区：
文献类型：
--
作者：
Cook DL;Bookstein FL;Gennari JH
随着生物医学研究人员努力整合空间时间尺度和生物医学领域的数据和分析，他们通过计算本体学认识了格式化语言和术语的好处。在本文中，没有校长的物理特性本体论，富集，体积，流速。 （OPB），是针对生物医学数据集和分析模型的生物物理含量注释的经典物理学的参考文献。参考可用上部本体的计算本体。生物医学数据集和计算模型，我们讨论了OPB框架将如何促进生物医学知识整合。
As biomedical investigators strive to integrate data and analyses across spatiotemporal scales and biomedical domains, they have recognized the benefits of formalizing languages and terminologies via computational ontologies. Although ontologies for biological entities—molecules, cells, organs—are well-established, there are no principled ontologies of physical properties—energies, volumes, flow rates—of those entities. In this paper, we introduce the Ontology of Physics for Biology (OPB), a reference ontology of classical physics designed for annotating biophysical content of growing repositories of biomedical datasets and analytical models. The OPB's semantic framework, traceable to James Clerk Maxwell, encompasses modern theories of system dynamics and thermodynamics, and is implemented as a computational ontology that references available upper ontologies. In this paper we focus on the OPB classes that are designed for annotating physical properties encoded in biomedical datasets and computational models, and we discuss how the OPB framework will facilitate biomedical knowledge integration.
影响因子：
14.9
作者：
Degtyarenko K;de Matos P;Ennis M;Hastings J;Zbinden M;McNaught A;Alcántara R;Darsow M;Guedj M;Ashburner M
通讯作者：
Ashburner M
影响因子：
14.9
作者：
UniProt Consortium
通讯作者：
UniProt Consortium
DOI：
10.1098/rsta.2008.0089
发表时间：
2008-09-13
影响因子：
5
作者：
Fenner, J. W.;Brook, B.;Viceconti, M.
通讯作者：
Viceconti, M.