FINE STRUCTURE OF EPENDYMA IN BRAIN OF RAT
FINE STRUCTURE OF EPENDYMA IN BRAIN OF RAT
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DOI：
10.1083/jcb.19.2.415
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发表时间：
1963-01-01
影响因子：
7.8
通讯作者：
PALAY, SL
中科院分区：
文献类型：
--
作者：
BRIGHTMAN, MW;PALAY, SL
大鼠脑的纤毛室管膜由一层上皮细胞组成，其腔表面反射在纤毛轴和许多不规则尺寸的外翻上。相邻细胞质膜的相对直的侧面部分在离散的位点融合形成五层连接或封闭小带，从而消除细胞间隙。这些融合通常发生在游离表面以下的某个距离处，或者独立地或者与第二个细胞间连接（即粘附小带）连续地发生。管腔连接处通常由粘连小带形成，偶尔由闭合小带形成。细颗粒状和丝状的细胞质含有核上致密体，其中一些可能是溶酶体和核周丝的致密螺旋，这些螺旋将束束发送到侧质膜。细胞质的顶端区域含有相邻纤毛的基体复合体。这些复合体包括一个有条纹的基足和短的、无条纹的小根，这些小根从每个基体的壁上发出。小根终止于基体近端附近的颗粒区，邻近的区域可能有形状各异的条纹状团块。相邻纤毛的基体复合体的所有成分是彼此独立的。
The ciliated ependyma of the rat brain consists of a sheet of epithelial cells, the luminal surface of which is reflected over ciliary shafts and numerous evaginations of irregular dimensions. The relatively straight lateral portions of the plas-maelemma of contiguous cells are fused at discrete sites to form five-layered junctions or zonulae occludentes which obliterate the intercellular space. These fusions occur usually at some distance below the free surface either independently or in continuity with a second intercellular junction, the zonula adhaerens. The luminal junction is usually formed by a zonula adhaerens or, occasionally, by a zonula occludens. The finely granular and filamentous cytoplasm contains supranuclear dense bodies, some of which are probably lysosomes and dense whorls of perinuclear filaments which send fascicles toward the lateral plasmalemma. The apical regions of the cytoplasm contain the basal body complexes of neighboring cilia. These complexes include a striated basal foot and short, non- striated rootlets emanating from the wall of each basal body. The rootlets end in a zone of granules about the proximal region of the basal body, adjacent to which may lie a striated mass of variable shape. All components of the basal body complex of adjacent cilia are independent of each other.