A Quantitative Examination of the Detection Sensitivities of Proton-Transfer Reaction Mass Spectrometry for Gaseous 2-Propanol and Acetic Acid
A Quantitative Examination of the Detection Sensitivities of Proton-Transfer Reaction Mass Spectrometry for Gaseous 2-Propanol and Acetic Acid
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DOI：
10.1246/bcsj.20100043
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发表时间：
2010-08-15
影响因子：
4
通讯作者：
Tanimoto, Hiroshi
中科院分区：
文献类型：
--
作者：
Inomata, Satoshi;Tanimoto, Hiroshi
系统地考察了质子转移反应质谱在5种不同动能下对异丙醇和乙酸的检测灵敏度。乙酸的检测灵敏度与从实验和理论上获得的H3 O+与乙酸反应的速率常数计算的灵敏度吻合得很好。然而，2-丙醇的检测灵敏度是相当小的计算值相比。在氘标记研究中，在H3 O+与（CD 3）（2）CHOH反应中，在m/z 20处清楚地观察到H2 DO+离子的形成，而在H3 O+与CD 3C（O）OH反应中未观察到H2 DO+的形成。我们得出结论，2-丙醇的实验和计算的检测灵敏度之间的差异是由于反应通道，再现H3 O+离子与2-丙醇反应过程中。
The detection sensitivities of proton-transfer reaction mass spectrometry for isobaric 2-propanol and acetic acid were examined systematically at five different kinetic energies. The detection sensitivity for acetic acid was in good agreement with the sensitivities calculated from the experimentally and theoretically obtained rate constants for the reaction of H3O+ with acetic acid. However, the detection sensitivity for 2-propanol was quite small compared with the calculated values. In deuterium-labeling studies, the formation of H2DO+ ions at m/z 20 in the reaction of H3O+ with (CD3)(2)CHOH was clearly observed, whereas the formation of H2DO+ was not observed in the reaction of H3O+ with CD3C(O)OH. We concluded that the difference between the experimental and calculated detection sensitivities for 2-propanol was attributed to a reaction channel that reproduced H3O+ ion during the reaction of H3O+ with 2-propanol.