The Cardiovascular Research Network A New Paradigm for Cardiovascular Quality and Outcomes Research
The Cardiovascular Research Network A New Paradigm for Cardiovascular Quality and Outcomes Research
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DOI：
10.1161/circoutcomes.108.801654
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发表时间：
2008-11-01
影响因子：
6.9
通讯作者：
Gurwitz, Jerry H.
中科院分区：
文献类型：
--
作者：
Go, Alan S.;Magid, David J.;Gurwitz, Jerry H.
背景-明确需要更系统地了解心血管疾病的流行病学、诊断和管理。更强大的数据也需要如何以及临床试验转化为当代社区的做法和相关的资源使用，成本和outcomes.Methods和结果-国家心脏，肺，血液研究所最近建立了心血管研究网络，这是一个新的范式来评估流行病学，护理质量，和心血管疾病的结果，并使用基于社区的模式进行未来的临床试验。该网络包括15个地理分布的健康计划，有专门的研究中心，国家心脏，肺和血液研究所的代表，以及一个外部合作和咨询委员会。心血管研究网络网站提供了补充内容和方法专业知识，以及通过各种医疗保健提供模式接受治疗的约1100万人的多样化人群。每个研究中心丰富的电子数据库（例如，社会人口统计学特征、住院和门诊诊断和程序、药房、实验室和成本数据）正在被映射，以创建标准化的虚拟数据仓库，以促进快速有效的大规模研究。最初的项目集中在（1）高血压的识别和管理，（2）华法林治疗的质量和结果，和（3）使用，结果，和植入式心律转复deliverators.Conclusions-The心血管研究网络的成本代表了一种新的范式，在社区人群中的心血管护理质量和结果的研究方法。其独特的能力，纵向大型，不同的人群将产生新的见解，当代疾病和风险因素的监测，管理，结果和成本。心血管研究网络旨在成为国家研究合作伙伴的首选，以改善心血管疾病的预防，诊断，治疗和结果。(Circ血管定性结局。2008;1：138-147）。
Background-A clear need exists for a more systematic understanding of the epidemiology, diagnosis, and management of cardiovascular diseases. More robust data are also needed on how well clinical trials are translated into contemporary community practice and the associated resource use, costs, and outcomes.Methods and Results-The National Heart, Lung, and Blood Institute recently established the Cardiovascular Research Network, which represents a new paradigm to evaluate the epidemiology, quality of care, and outcomes of cardiovascular disease and to conduct future clinical trials using a community-based model. The network includes 15 geographically distributed health plans with dedicated research centers, National Heart, Lung, and Blood Institute representatives, and an external collaboration and advisory committee. Cardiovascular research network sites bring complementary content and methodological expertise and a diverse population of approximate to 11 million individuals treated through various health care delivery models. Each site's rich electronic databases (eg, sociodemographic characteristics, inpatient and outpatient diagnoses and procedures, pharmacy, laboratory, and cost data) are being mapped to create a standardized virtual data warehouse to facilitate rapid and efficient large-scale research studies. Initial projects focus on (1) hypertension recognition and management, (2) quality and outcomes of warfarin therapy, and (3) use, outcomes, and costs of implantable cardioverter defibrillators.Conclusions-The Cardiovascular Research Network represents a new paradigm in the approach to cardiovascular quality of care and outcomes research among community-based populations. Its unique ability to characterize longitudinally large, diverse populations will yield novel insights into contemporary disease and risk factor surveillance, management, outcomes, and costs. The Cardiovascular Research Network aims to become the national research partner of choice for efforts to improve the prevention, diagnosis, treatment, and outcomes of cardiovascular diseases. (Circ Cardiovasc Qual Outcomes. 2008;1:138-147.)