t-Haplotypes of the mouse may involve a change in intercalary DNA
t-Haplotypes of the mouse may involve a change in intercalary DNA
复制标题
小鼠的t-单倍型可能涉及居间DNA的变化
作者：
M. Lyon;E. P. Evans;S. E. Jarvis;I. Sayers
小鼠天然存在的 t 单倍型表现出一系列独特的遗传特性，包括对 17 号染色体片段 T 和 H-2 基因座之间交叉的强烈抑制。对突变单倍型的遗传学研究表明，所观察到的对减数分裂和胚胎发育的影响可能是由于相关染色体区域（带 17B）中闰 DNA (iDNA) 形式的改变所致。
The naturally occurring t-haplotypes of the mouse exhibit a set of peculiar genetic properties, including strong suppression of crossing over in the segment of chromosome 17 between the loci of T and H–2. Study of the genetics of mutant haplotypes suggests that the observed effects on meiosis and embryonic development may be due to an altered form of intercalary DNA (iDNA) in the relevant chromosomal region (band 17B).