Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates
Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates
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DOI：
10.1016/s0006-8993(97)00337-5
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发表时间：
1997-05-23
期刊：
影响因子：
2.9
通讯作者：
Block, GD
中科院分区：
文献类型：
--
作者：
Herzog, ED;Geusz, ME;Block, GD
哺乳动物下丘脑的视交叉上核（SCN）起昼夜节律起搏器的作用。本研究使用多微电极板同时测量培养小鼠SCN内多个部位的细胞外动作电位活动。分离的小鼠SCN内的神经元在培养数周内表达了自发放电率的昼夜节律。
The suprachiasmatic nucleus (SCN) of the mammalian hypothalamus functions as a circadian pacemaker. This study used multimicroelectrode plates to measure extracellular action potential activity simultaneously from multiple sites within the cultured mouse SCN. Neurons within the isolated mouse SCN expressed a circadian rhythm in spontaneous firing rate for weeks in culture.