Atrioesophageal fistula formation with cryoballoon ablation is most commonly related to the left inferior pulmonary vein
Atrioesophageal fistula formation with cryoballoon ablation is most commonly related to the left inferior pulmonary vein
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DOI：
10.1016/j.hrthm.2016.10.018
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发表时间：
2017-02-01
期刊：
影响因子：
5.5
通讯作者：
Koneru, Jayanthi N.
中科院分区：
文献类型：
--
作者：
John, Roy M.;Kapur, Sunil;Koneru, Jayanthi N.
背景使用冷冻球囊进行肺静脉隔离时已报告了附带损伤。目的本研究的目的是确定使用冷冻球囊后与心房食管瘘（AEF）相关的发生率和特征。方法自2011年以来使用冷冻球囊报告的AEF病例收集自制造商与用户机构设备使用（MAUDE）数据库、出版物、和制造商的数据库将最低球囊温度与接受冷冻球囊消融且未形成AEF的匹配对照患者进行比较。AEF的位置进行了比较，AEF相关的射频ablation.RESULTS共11例AEF从全球范围内的经验，超过120,000例。平均年龄为60岁（范围31-78岁），80%的患者为男性。虽然平均最低球囊温度在AEF患者和无AEF患者之间没有差异，（-58.5 ℃ +/- 7.2 ℃ vs - 56 ℃ +/- 2.6 ℃，P = NS），AEF患者的球囊充盈时间更长（238.8 +/- 54.8秒vs非AEF组的178.1 +/- 37.5秒，P
BACKGROUND Collateral damage has been reported with use of the cryoballoon for pulmonary vein isolation.OBJECTIVE The purpose of this study was to determine the incidence and characteristics associated with atrioesophageal fistula (AEF) after cryoballoon use.METHODS Cases of AEF reported with use of the cryoballoon since 2011 were collected from the Manufacturer and User Facility Device Experience (MAUDE) database, publications, and the manufacturer's database. Lowest balloon temperatures were compared with matched control patients undergoing cryoballoon ablation without AEF formation. Location of AEF was compared with AEF associated with radiofrequency ablation.RESULTS A total of 11 cases of AEF were identified from a worldwide experience that exceed 120,000 cases. Mean age was 60 (range 31-78 years), and 80% of patients were male. Although mean lowest balloon temperatures were no different between patients with AEF and those with no AEF (-58.5 degrees C +/- 7.2 degrees C vs - 56 degrees C +/- 2.6 degrees C, P = NS), balloon inflation times were longer in patients with AEF (238.8 +/- 54.8 seconds vs 178.1 +/- 37.5 seconds in the non-AEF group, P