Use of estrogen supplementation is associated with higher quality of life scores in women with cystic fibrosis.
Use of estrogen supplementation is associated with higher quality of life scores in women with cystic fibrosis.
复制标题
使用雌激素补充剂与囊性纤维化女性较高的生活质量评分相关。
DOI：
10.1016/j.jcte.2021.100292
复制
发表时间：
2022-03
影响因子：
3
通讯作者：
Tangpricha V
中科院分区：
文献类型：
--
作者：
Wu M;Arora N;Sueblinvong V;Hunt WR;Tangpricha V
补充雌激素与CF女性的生活质量评分较高相关。患有CF的女性使用雌激素来调节月经、避孕和缓解月经症状。无论是否补充雌激素，患有CF的女性都有相似的活动性评分。使用雌激素的CF女性与未使用雌激素的女性性功能障碍的发生率相似。囊性纤维化（CF）妇女雌激素补充剂的使用和生活质量的关系还没有得到很好的表征。在这项横断面研究中，CF妇女在常规CF诊所就诊期间完成生活质量问卷。使用雌激素补充剂与CF量表修订版（CFQ-R）所有领域的生活质量评分较高相关，在角色限制和呼吸领域具有显著性。大多数目前没有使用雌激素补充剂的参与者以前使用过雌激素补充剂。大多数参与者使用雌激素来调节月经，防止怀孕和控制月经前后的症状。雌激素补充剂的使用与生活空间移动性或性功能障碍筛查的差异无关。这是迄今为止调查雌激素补充剂与CF女性生活质量之间关系的最大规模研究。需要前瞻性随机研究来阐明雌激素补充与CF妇女生活质量的关系。
Supplemental estrogen was associated with higher quality of life scores in women with CF. Women with CF used estrogen for menses regulation, contraception & menstrual symptoms. Regardless of estrogen supplementation, women with CF had similar mobility scores. Women with CF using estrogen had similar rates of sexual dysfunction to those not using estrogen. The association of estrogen supplementation use and quality of life in women with cystic fibrosis (CF) is not well characterized. In this cross-sectional study, women with CF completed quality of life questionnaires during a routine CF clinic visit. The use of estrogen supplementation was associated with higher quality of life scores in all domains of the CF questionnaire-revised (CFQ-R) and was significant in the role limitations and respiratory domains. Most participants who were not currently using estrogen supplementation had previously used estrogen supplementation. Most participants had used estrogen to regulate menses, prevent pregnancy and control symptoms around menses. Use of estrogen supplementation was not associated with differences in life-space mobility or screening for sexual dysfunction. This is the largest study to date investigating the association of estrogen supplementation and quality of life in women with CF. Prospective randomized studies are needed to clarify the association of estrogen supplementation and quality of life in women with CF.
登录
查看更多内容
囊性纤维化女性的雌激素治疗与骨骼健康之间的关系。
DOI：
10.1016/j.amjms.2020.06.005
发表时间：
2020-11
期刊：
The American journal of the medical sciences
影响因子：
--
作者：
Wu M;Bettermann EL;Arora N;Hunt WR;McCracken C;Tangpricha V
通讯作者：
Tangpricha V
影响因子：
120.7
作者：
Manson, JoAnn E.;Chlebowski, Rowan T.;Stefanick, Marcia L.;Aragaki, Aaron K.;Rossouw, Jacques E.;Prentice, Ross L.;Anderson, Garnet;Howard, Barbara V.;Thomson, Cynthia A.;LaCroix, Andrea Z.;Wactawski-Wende, Jean;Jackson, Rebecca D.;Limacher, Marian;Margolis, Karen L.;Wassertheil-Smoller, Sylvia;Beresford, Shirley A.;Cauley, Jane A.;Eaton, Charles B.;Gass, Margery;Hsia, Judith;Johnson, Karen C.;Kooperberg, Charles;Kuller, Lewis H.;Lewis, Cora E.;Liu, Simin;Martin, Lisa W.;Ockene, Judith K.;O'Sullivan, Mary Jo;Powell, Lynda H.;Simon, Michael S.;Van Horn, Linda;Vitolins, Mara Z.;Wallace, Robert B.
通讯作者：
Wallace, Robert B.
影响因子：
8.3
作者：
Holtrop, Melanie;Heltshe, Sonya;Jain, Raksha
通讯作者：
Jain, Raksha
影响因子：
9.6
作者：
Quittner, Alexandra L.;Modi, Avani C.;Montgomery, A. Bruce
通讯作者：
Montgomery, A. Bruce
影响因子：
1.7
作者：
Gottlieb, Eric Raphael;Smith, Elisabeth Christine;Tangpricha, Vin
通讯作者：
Tangpricha, Vin