Pain responses of Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation: Manchester Pascal Study, MAPASS report 2
Pain responses of Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation: Manchester Pascal Study, MAPASS report 2
复制标题
DOI：
10.1136/bjo.2009.176677
复制
发表时间：
2010-11-01
影响因子：
4.1
通讯作者：
Stanga, P. E.
中科院分区：
文献类型：
--
作者：
Muqit, M. M. K.;Marcellino, G. R.;Stanga, P. E.
目的评价帕斯卡20ms多点和100ms单点全视网膜光凝(PRP)后的疼痛反应。未经治疗的增殖性糖尿病视网膜病变患者24例40只眼，随机分为20和100ms，外用0.4%羟布普鲁卡因治疗。一名蒙面评分者在治疗1h内(数字疼痛评分(NPS))和治疗后1个月(数字头痛评分(NHS))进行疼痛问卷调查。主要结果评估是PRP后即刻的NPS。结果20ms PRP的平均激光强度(4.8J/cm(2))显著低于100ms PRP(11.8J/cm(2)；P<0.05)。
Aims To evaluate pain responses following Pascal 20 ms multi-spot and 100 ms single-spot panretinal photocoagulation (PRP).Methods Single-centre randomised clinical trial. 40 eyes of 24 patients with treatment-naive proliferative diabetic retinopathy randomised to 20 and 100 ms PRP under topical 0.4% oxybuprocaine. A masked grader used a pain questionnaire within 1 h (numerical pain score (NPS)) and 1 month after treatment (numerical headache score (NHS)). Primary outcome measure was NPS immediately post-PRP. Secondary outcome measures were mean NHS scores and levels of photophobia reported within 4 weeks of primary PRP.Results Mean laser fluence was significantly lower using 20 ms PRP (4.8 J/cm(2)) compared to 100 ms PRP (11.8 J/cm(2); p