Aqueous Synthesis of CdTe/CdSe Core/Shell Quantum Dots as pH-Sensitive Fluorescence Probe for the Determination of Ascorbic Acid
Aqueous Synthesis of CdTe/CdSe Core/Shell Quantum Dots as pH-Sensitive Fluorescence Probe for the Determination of Ascorbic Acid
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DOI：
10.1007/s10895-010-0788-9
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发表时间：
2011-05
影响因子：
2.7
通讯作者：
Shanshan Yang;C. Ren;Zhenyang Zhang;J. Hao;Qin Hu;Xinguo Chen
中科院分区：
文献类型：
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作者：
Shanshan Yang;C. Ren;Zhenyang Zhang;J. Hao;Qin Hu;Xinguo Chen
通过控制回流时间和壳层材料的用量，在水溶液中合成了不同尺寸的巯基乙酸（TGA）修饰的CdTe/CdSe核/壳量子点。这种类型的量子点用于商业片剂中抗坏血酸的灵敏和选择性测定。在最佳条件下，抗坏血酸浓度在4.0 ~ 64.0 μg/mL范围内与荧光强度呈良好的线性关系，相关系数为0.9968。检测限为2.4 μg/mL。方法用于维生素C片和维生素C银翘丸中抗坏血酸的测定，结果满意。
By controlling the reflux time and the quantity of the shell materials, different sizes of thioglycollic acid (TGA) modified CdTe/CdSe core/shell quantum dots were synthesized in aqueous solution. This type of QDs was used for sensitive and selective determination of ascorbic acid in commercial tablets. Under optimal conditions, a good linearity was observed between the relative fluorescence (FL) intensity and the concentration of ascorbic acid in the range of 4.0 to 64.0 μg/mL with a correlation coefficient of 0.9968. The limit of detection was 2.4 μg/mL. This method was applied to the determination of the ascorbic acid in Vitamin C tablets and Vitamin C Yinqiao pills, and satisfactory results were obtained.