Women's health in early pregnancy: Findings from an Australian nulliparous cohort study
Women's health in early pregnancy: Findings from an Australian nulliparous cohort study
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DOI：
10.1111/j.1479-828x.2010.01204.x
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发表时间：
2010-10-01
影响因子：
1.7
通讯作者：
Perlen, Susan
中科院分区：
文献类型：
--
作者：
Gartland, Deirdre;Brown, Stephanie;Perlen, Susan
背景：孕期严重孕产妇发病率已知较多，但很少有人关注妊娠本身对妇女总体健康和福祉的影响。目的：调查妊娠早期妇女的总体健康和幸福感，并检查孕妇年龄与妇女身心健康的关系。方法：对多中心未孕队列研究的基线数据进行横断面分析。基线问卷包括SF-36健康状况量表和评估一系列常见孕产妇健康问题的个别项目。结果：共有1507名符合条件的妇女在怀孕早期(平均孕周15周，范围6-24周)返回基线问卷，年龄18-49岁(平均年龄30.1岁)。研究参与者报告说，与年龄和性别标准化的人口平均值相比，除一般健康外，所有SF-36量表的健康状况都要差得多。三分之二的女性(68%)报告了三个或三个以上的健康问题，最常见的是疲惫(87%)、恶心(%)、背痛(46%)、便秘(44%)和严重头痛/偏头痛(30%)。年轻女性(18-24岁)的SF-36得分(自我健康状况较差)显著低于女性(P<；0.03)。在调整了社会人口因素后，母亲的年龄与妇女的心理和身体部分得分仍然显著正相关。年轻女性报告的健康问题显著多于女性(4.39和3.27，平均差异=1.12，95%CI0.75-1.79，P<；0.001)。结论：常见的妊娠症状对女性早孕的身心健康有显著影响，其中以年轻女性的影响最大。
Background:Much is known about severe maternal morbidity during pregnancy, but there has been little attention paid to the impact of pregnancy itself on women's general health and well-being.Aim:To investigate women's general health and well-being in early pregnancy and examine the relationship between maternal age and women's physical and mental health.Method:Cross-sectional analysis of baseline data from a multicentre, prospective nulliparous pregnancy cohort study. The baseline questionnaire included the SF-36 health status measure and individual items assessing a range of common maternal health issues.Results:A total of 1507 eligible women returned baseline questionnaires in early pregnancy (mean gestation 15 weeks, range 6-24 weeks) ranging from 18 to 49 years of age (mean age 30.1 years). Study participants reported significantly poorer health compared with age and gender-standardised population means on all SF-36 scales except general health. Two-thirds of women (68%) reported three or more health issues, the most common being exhaustion (87%), nausea (64%), back pain (46%), constipation (44%) and severe headaches/migraines (30%). Younger women (18-24 years) had significantly lower SF-36 scores (poorer self perceived health) compared with women >= 35 (P < 0.03). After adjusting for socio-demographic factors, maternal age remained significantly positively associated with women's mental and physical component scores. Younger women reported significantly more health issues than women >= 35 (4.39 and 3.27, mean difference = 1.12, 95% CI 0.75-1.79, P < 0.001).Conclusions:Common pregnancy symptoms have a marked impact on women's physical and mental health in early pregnancy, with the greatest impact apparent for younger women.