GPCRDB: information system for G protein-coupled receptors.

GPCRDB: information system for G protein-coupled receptors.
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DOI:
10.1093/nar/gkq1009
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发表时间:
2011-01
影响因子:
14.9
通讯作者:
Vriend G
Vriend G
中科院分区:
生物学2区
文献类型:
--
作者:
Vroling B;Sanders M;Baakman C;Borrmann A;Verhoeven S;Klomp J;Oliveira L;de Vlieg J;Vriend G

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GPCRDB是一个分子类别特异性信息系统(MCSIS),它收集、组合、验证和传播大量关于G蛋白偶联受体(GPCR)的异质性数据。GPCRDB包含关于序列、配体结合常数、突变和寡聚体的实验数据,以及许多不同类型的计算衍生数据,例如多重序列比对和同源性模型。GPCRDB通过多种不同的访问方法提供对数据的访问。它提供可视化和分析工具,以及一些查询系统。数据每月自动更新。GPCRDB可在http://www.gpcr.org/7tm/网站上找到。
The GPCRDB is a Molecular Class-Specific Information System (MCSIS) that collects, combines, validates and disseminates large amounts of heterogeneous data on G protein-coupled receptors (GPCRs). The GPCRDB contains experimental data on sequences, ligand-binding constants, mutations and oligomers, as well as many different types of computationally derived data such as multiple sequence alignments and homology models. The GPCRDB provides access to the data via a number of different access methods. It offers visualization and analysis tools, and a number of query systems. The data is updated automatically on a monthly basis. The GPCRDB can be found online at http://www.gpcr.org/7tm/.
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