Anthropometric predictors of coronary heart disease and total mortality: findings from the US Railroad Study.

Anthropometric predictors of coronary heart disease and total mortality: findings from the US Railroad Study.
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冠心病和总死亡率的人体测量预测因素:美国铁路研究的结果。

DOI:
10.1093/oxfordjournals.aje.a116031
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发表时间:
1991
影响因子:
5
通讯作者:
Nelson,ET
Nelson,ET
中科院分区:
医学2区
文献类型:
--
作者:
Yao,CH;Slattery,ML;JacobsJr,DR;Folsom,AR;Nelson,ET

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来自美国铁路研究的前瞻性数据被用于调查最初无心血管疾病的男性中几个人体测量学变量与冠心病和全因死亡率的关系。中年男性在1957-1960年接受了检查,并一直跟踪到1977年或死亡。人体测量指标全身脂肪(体重指数和肩胛下和三头肌皮褶总和)和中心体脂肪(胸围/肩峰(肩部)直径和胸围/站立高度的比值)与年龄校正的冠心病死亡率显著直接相关。当收缩压、血清胆固醇、吸烟和肺活量也被考虑在内时,胸围/肩峰直径的比值仍然与冠心病死亡率显著相关。总的、中心的和周围的体脂与全因死亡率呈“U”形关系。测量中心体脂肪与外周体脂肪的比率与死亡率的相关性不一致。这些结果表明,某些人体测量,特别是那些可能表明中心性肥胖,是正相关的致命性冠心病的发展和二次相关的全因死亡率。
Prospective data from the US Railroad Study were used to investigate the relations of several anthropometnc variables to coronary heart disease and all-cause mortality in males initially free of cardiovascular disease. Middle-aged men were examined in 1957–1960 and followed until 1977 or death. Anthropometric indicators of total body fat (body mass index and the sum of the subscapular and triceps skinfolds) and central body fat(the ratios chest circumference/biacromial (shoulder) diameter, and chest circumference/standing height) were significantly and directly associated with age-adjusted coronary heart disease mortality. When systolic blood pressure, serum cholesterol, cigarette smoking, and vital capacity were also taken into account, the ratio chest circumference/biacromial diameter remained significantly associated with coronary heart disease mortality. Total, central, and peripheral body fat had a “U”-shaped relation with all-cause mortality. Measures of the ratio of central to peripheral body fat were inconsistently related to mortality. These results indicate that certain anthropometric measurements, especially those that may indicate central adiposity, are positively related to the development of fatal coronary heart disease and quadratically related to all-causes death rates.
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