THE HIPPOCAMPAL SYSTEM AND DECLARATIVE MEMORY IN ANIMALS
THE HIPPOCAMPAL SYSTEM AND DECLARATIVE MEMORY IN ANIMALS
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DOI：
10.1162/jocn.1992.4.3.217
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发表时间：
1992-06-01
影响因子：
3.2
通讯作者：
EICHENBAUM, H
中科院分区：
文献类型：
--
作者：
EICHENBAUM, H
理论论证和经验数据支持这一假设，即海马体系统支持动物和人类的陈述性记忆能力。这一观点是通过确定人类陈述性记忆的突出特征，并通过使用动物实验损伤和单单位记录研究来操作和评估这些特征而提出的。首先，海马体的处理对任何特定类别的学习材料都不是选择性的；相反，它支持记忆中各种信息之间的比较，从而产生项目之间的关键关系的表征。相反，个体表征在海马体系统之外得到支持。其次，依赖于海马体的关系记忆表征涉及一种灵活的组织，允许在新的情况下从记忆中进行推断。相反，海马区独立的个体表征只能支持在原始学习过程中获得的程序的重复。神经心理学和神经生理学的发现之间的对应关系表明，海马体表征的这些特性如何支持跨行为范式和跨物种的陈述性记忆。
Theoretical arguments and empirical data are presented in favor of the hypothesis that the hippocampal system supports a declarative memory capacity in animals as well as humans. This view is advanced by identifying mo prominent characteristics of human declarative memory and by operationalizing and evaluating them using both experimental lesion and single unit recording studies on animals. First, hippocampal processing is not selective to any particular category of learning materials; instead, it supports comparisons among all kinds of information in memory, resulting in a representation of critical relations between items. Conversely, individual representations are supported outside the hippocampal system. Second, hippocampal-dependent, relational memory representations involve a flexible organization that permits inferences from memory in novel situations. Conversely, hippocampal-independent individual representations can support only repetition of procedures acquired during original learning. Correspondences between the neuropsychological and neurophysiological findings presented serve to indicate how these properties of hippocampal representation support declarative memory across behavioral paradigms and across species.