Noninvasive measurement of time-varying three-dimensional relative pressure fields within the human heart
Noninvasive measurement of time-varying three-dimensional relative pressure fields within the human heart
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DOI：
10.1115/1.1468866
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发表时间：
2002-06-01
影响因子：
1.7
通讯作者：
Karlsson, M
中科院分区：
文献类型：
--
作者：
Ebbers, T;Wigström, L;Karlsson, M
了解心脏血流模式在心血管功能评估中非常重要。结合速度测量和计算力学方法，给出了人体左心室内的三维流场和相对压力场。利用时间分辨三维相衬MRI测量了正常人心脏左心房和左心室的速度场。随后，时间分辨的三维相对压力计算从这个速度场使用的压力泊松方程。心脏压力和血流现象的无创性同步评估是研究心脏流体动力学的重要新工具。
Understanding cardiac blood flow patterns is important in the assessment of cardiovascular function. Three-dimensional flow and relative pressure fields within the human left ventricle are demonstrated by combining velocity measurements with computational mechanics methods. The velocity field throughout the left atrium and ventricle of a normal human heart is measured using time-resolved three-dimensional phase-contrast MRI. Subsequently, the time-resolved three-dimensional relative pressure is calculated from this velocity field using the pressure Poisson equation. Noninvasive simultaneous assessment of cardiac pressure and flow phenomena is an important new tool for studying cardiac fluid dynamics.