How reliable are human hair reference intervals for trace elements?
How reliable are human hair reference intervals for trace elements?
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DOI：
10.1016/s0048-9697(98)00185-5
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发表时间：
1998-07-11
影响因子：
9.8
通讯作者：
da Silveira, CLP
中科院分区：
文献类型：
--
作者：
Miekeley, N;Carneiro, MTWD;da Silveira, CLP
电感耦合等离子体质谱法（ICP-MS）用于测定的主要和微量元素浓度的头皮头发样本的人口组（N = 1091）的里约热内卢市。根据这些结果，计算了几种微量元素（例如B、V、Co、Ge、Mo、Au、As、Se、Sb、Th）的初步“正常”或参考区间，但也计算了一些微量元素（例如Ca、Mg）的初步“正常”或参考区间，这些元素与五个临床实验室使用电感耦合等离子体原子发射光谱法（ICP-AES）发表的数据不一致。ICP-AES在常规毛发分析中的局限性通过两种方法的检测限比较和两个实验室相互比较的结果来说明。从这些数据中可以明显看出，必须极其谨慎地使用已发表的参考区间，并且基于ICP-MS技术产生的可靠数据对其进行紧急修订是极其重要的。(C)1998 Elsevier Science B. V.保留所有权利。
Inductively coupled plasma mass spectrometry (ICP-MS) was used for the determination of major and trace element concentrations in scalp hair samples from a population group (N = 1091) of Rio de Janeiro city. From these results, preliminary 'normal' or reference intervals were calculated which are for several trace elements (e.g. B, V, Co, Ge, Mo, Au, As, Se, Sb, Th), but also for some minor elements (e.g. Ca, Mg) in disaccord with data published by five clinical laboratories which used inductively coupled plasma atomic emission spectrometry (ICP-AES). The limitations of ICP-AES in routine hair analysis is shown by comparison of detection limits for both methods and by results from two laboratory intercomparison exercises. It is evident from these data that published reference intervals have to be used with extreme caution and that their urgent revision, based on reliable data produced by the ICP-MS technique, is of extreme importance. (C) 1998 Elsevier Science B.V. All rights reserved.