A 31-year-old woman with rash, fever, and hypotension - Acute necrotizing eosinophilic myocarditis associated with a systemic necrotizing inflammatory process also involving skeletal muscle, the liver, and the spinal cord, most consistent with a severe drug-induced hypersensitivity reaction.
A 31-year-old woman with rash, fever, and hypotension - Acute necrotizing eosinophilic myocarditis associated with a systemic necrotizing inflammatory process also involving skeletal muscle, the liver, and the spinal cord, most consistent with a severe drug-induced hypersensitivity reaction.
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DOI：
10.1056/nejmcpc079030
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发表时间：
2007-11-22
影响因子：
158.5
通讯作者：
Baggish, Aaron
中科院分区：
文献类型：
--
作者：
Sabatine, Marc S.;Poh, Kian-Keong;Baggish, Aaron
A 31-year-old woman was admitted to this hospital because of rash, fever, and facial swelling that developed after the administration of modafinil for the treatment of fatigue associated with multiple sclerosis. Several hours after admission, chest discomfort and hypotension developed, ST-segment elevation was present on the electrocardiogram, and biomarkers of cardiac necrosis were elevated. Echocardiography disclosed a pericardial effusion and left ventricular dysfunction. A diagnostic procedure was performed.
