Treatment regimen adherence in pediatric gastroenterology.
Treatment regimen adherence in pediatric gastroenterology.
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DOI：
10.1097/mpg.0b013e318175dda1
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发表时间：
2008-11
影响因子：
2.9
通讯作者：
Crandall WV
中科院分区：
文献类型：
--
作者：
Hommel KA;Mackner LM;Denson LA;Crandall WV
回顾和批判性评价与儿科胃肠病（特别是炎症性肠病和乳糜泻）依从性相关的现有研究，并为未来的研究开发提供建议。使用PubMed和PsychInfo电子数据库和相关文章的参考书目进行了无日期限制的文献检索。在不同治疗和评估方法中，炎症性肠病和乳糜泻的依从率分别为16%-62%和5%-70%;通常未报告不依从频率。用于评估依从性的措施包括自我报告、访谈、饮食记录和生物测定方法，每种措施都证明了优势和局限性。有限的证据表明，这两种疾病人群的依从性与患者和家庭行为因素有关，而不依从性与疾病预后不良有关。在目前的文献中，对不依从的治疗结果研究很少。未来的研究应集中在完善的评估方法，纵向检查遵守和伴随的行为因素，测试理论模型的遵守，并制定有效的治疗不遵守。
To review and critically evaluate the extant research pertaining to adherence in pediatric gastroenterological diseases, particularly inflammatory bowel disease and celiac disease, and to provide recommendations for future research development. A literature search with no date restriction was conducted using PubMed and PsychInfo electronic databases and bibliographies of relevant articles. Adherence rates in inflammatory bowel disease and celiac disease range considerably from 16% to 62% and 5% to 70%, respectively, across treatments and assessment method; nonadherence frequency was generally not reported. Measures used to assess adherence included self-report, interview, diet record, and bioassay methods, and each measure demonstrated strengths and limitations. Limited evidence suggests that adherence in both disease populations is related to patient and family behavioral factors and that nonadherence is related to poor disease outcome. Treatment outcome research for nonadherence is scant in the current literature. Future research should focus on refining assessment method, examining adherence and concomitant behavioral factors longitudinally, testing theoretical models of adherence, and developing efficacious treatments for nonadherence.