The MAOA gene predicts happiness in women.
The MAOA gene predicts happiness in women.
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DOI：
10.1016/j.pnpbp.2012.07.018
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发表时间：
2013-01-10
影响因子：
5.6
通讯作者：
Cohen P
中科院分区：
文献类型：
--
作者：
Chen H;Pine DS;Ernst M;Gorodetsky E;Kasen S;Gordon K;Goldman D;Cohen P
Psychologists, quality of life and well-being researchers have grown increasingly interested in understanding the factors that are associated with human happiness. Although twin studies estimate that genetic factors account for 35–50% of the variance in human happiness, knowledge of specific genes is limited. However, recent advances in molecular genetics can now provide a window into neurobiological markers of human happiness. This investigation examines association between happiness and monoamine oxidase A (MAOA) genotype. Data were drawn from a longitudinal study of a population-based cohort, followed for three decades. In women, low expression of MAOA (MAOA-L) was related significantly to greater happiness (0.261 SD increase with one L-allele, 0.522 SD with two L-alleles, P=0.002) after adjusting for the potential effects of age, gender, race, education, household income, marital status, employment status, mental disorder, physical health, relationship quality, religiosity, abuse history, recent negative life events and self-esteem use in linear regression models. In contrast, no such association was found in men. This new finding may help explain the gender difference on happiness and provide a link between MAOA and human happiness.
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影响因子：
9.8
作者：
Alesina, A;Di Tella, R;MacCulloch, R
通讯作者：
MacCulloch, R
影响因子：
11
作者：
Ducci, F.;Newman, T. K.;Goldman, D.
通讯作者：
Goldman, D.
影响因子：
56.9
作者：
Caspi, A;McClay, J;Poulton, R
通讯作者：
Poulton, R
DOI：
10.1523/jneurosci.2391-08.2008
发表时间：
2008-10-29
期刊：
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子：
--
作者：
Mickey BJ;Ducci F;Hodgkinson CA;Langenecker SA;Goldman D;Zubieta JK
通讯作者：
Zubieta JK
影响因子：
3.5
作者：
Chen, H;Cohen, P;Smailes, E
通讯作者：
Smailes, E