Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent
Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent
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DOI：
10.1016/s0960-894x(98)00728-8
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发表时间：
1999-01-18
影响因子：
2.7
通讯作者：
Upton, N
中科院分区：
文献类型：
--
作者：
Chan, WN;Evans, JM;Upton, N
对新型顺式和反式4-（取代氨基）苯并吡喃3-醇衍生物的优化，鉴定出SE-220453 20具有体内临床前中枢神经系统特征，可预测其潜在的抗偏头痛活性。1999爱思唯尔科学有限公司版权所有。
Optimisation of novel cis- and trans-4-(substituted-amido)benzopyran-3-ol derivatives has led to the identification of SE-220453 20 with an in vivo pre-clinical CNS profile predictive of potential antimigraine activity. (C) 1999 Elsevier Science Ltd. All rights reserved.