Has COVID-19 suppressed dengue transmission in Nepal?
Has COVID-19 suppressed dengue transmission in Nepal?
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DOI：
10.1017/s0950268822001790
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发表时间：
2022-11-18
影响因子：
4.2
通讯作者：
Morita, Kouichi
中科院分区：
文献类型：
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作者：
Pandey, Basu Dev;Tun, Mya Myat Ngwe;Pandey, Kishor;Dumre, Shyam Prakash;Bhandari, Pramananda;Pyakurel, Uttam Raj;Pokhrel, Nayanum;Dhimal, Meghanath;Gyanwali, Pardip;Culleton, Richard;Takamatsu, Yuki;Costello, Anthony;Morita, Kouichi
于二零二零年一月二十三日尼泊尔报告首例COVID-19病例后，于二零二零年至二零二一年录得三次主要疫情。截至2022年7月底，已报告986 596例COVID-19确诊病例和11 967例死亡病例，70. 5%的人口已接种至少两剂COVID-19疫苗。在大流行之前，大规模登革热病毒（DENV）疫情影响了77个地区中的68个地区，2019年记录了17932例病例和6例死亡。相比之下，该国的流行病学和疾病控制部门在大流行期间（2020年和2021年）分别报告了530例和540例登革热病例。此外，加德满都在2020年和2021年仅报告了63例登革热病例，显著低于2019年报告的1463例。血清学检测显示，在疫情期间，抗登革免疫球蛋白M抗体的阳性率为3. 2%，而在疫情之前为26. 9 -40%。需要持续分析登革热发病率，并进一步加强区域和国际层面的监测和合作，以充分了解登革热发病率/传播的减少是否由COVID-19大流行期间的行动限制所致。
Following the report of the first COVID-19 case in Nepal on 23 January 2020, three major waves were documented between 2020 and 2021. By the end of July 2022, 986 596 cases of confirmed COVID-19 and 11 967 deaths had been reported and 70.5% of the population had received at least two doses of a COVID-19 vaccine. Prior to the pandemic, a large dengue virus (DENV) epidemic affected 68 out of 77 districts, with 17 932 cases and six deaths recorded in 2019. In contrast, the country's Epidemiology and Disease Control Division reported 530 and 540 dengue cases in the pandemic period (2020 and 2021), respectively. Furthermore, Kathmandu reported just 63 dengue cases during 2020 and 2021, significantly lower than the 1463 cases reported in 2019. Serological assay showed 3.2% positivity rates for anti-dengue immunoglobulin M antibodies during the pandemic period, contrasting with 26.9–40% prior to it. Real-time polymerase chain reaction for DENV showed a 0.5% positive rate during the COVID-19 pandemic which is far lower than the 57.0% recorded in 2019. Continuing analyses of dengue incidence and further strengthening of surveillance and collaboration at the regional and international levels are required to fully understand whether the reduction in dengue incidence/transmission were caused by movement restrictions during the COVID-19 pandemic.