Enhanced mechanical properties and blood compatibility of PDMS/liquid crystal cross-linked membrane materials
Enhanced mechanical properties and blood compatibility of PDMS/liquid crystal cross-linked membrane materials
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PDMS/液晶交联膜材料的机械性能和血液相容性增强
DOI：
10.1016/j.jmbbm.2013.01.010
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发表时间：
2013-04-01
影响因子：
3.9
通讯作者：
Liu, Fanna
中科院分区：
文献类型：
--
作者：
Rao, Huaxin;Zhang, Ziyong;Liu, Fanna
以含乙烯基的聚二甲基硅氧烷（PDMS）和含不饱和键的液晶（LC）为基体材料，制备了一种新型的PDMS/LC交联膜。研究了不同液晶含量和不同液晶基团的PDMS/LC交联膜的力学性能、液晶性能和血液相容性。结果表明，与纯PDMS膜相比，膜的力学性能得到了显著提高。PDMS/LC交联膜具有较好的成膜性、较低的溶血率、较低的血小板粘附率和较好的抗凝血性能。此外，由于引入了双相液晶和优选的交联反应而没有副产物的应用，膜的机械性能和血液相容性可以同时且明显地增强。(C)2013爱思唯尔有限公司保留所有权利。
A novel polydimethylsiloxane/liquid crystal cross-linked membrane (PDMS/LC) was prepared by using PDMS containing vinyl groups and LCs containing unsaturated linkages as matrix materials. Mechanical properties, liquid crystalline performance and blood compatibility of the PDMS/LC cross-linked membrane containing different LC contents and LC groups were investigated, respectively. The results showed that mechanical properties of the membrane increased more significantly than those of pure PDMS membranes. The PDMS/LC cross-linked membrane also possessed better membrane-forming ability, lower hemolysis rate, less platelets adhesion and more favorable anticoagulant properties. Additionally, mechanical properties and blood compatibility of the membrane can be enhanced simultaneously and obviously due to the introduction of the cholesteric liquid crystals and the application of the preferred cross-linked reaction without byproducts. (C) 2013 Elsevier Ltd. All rights reserved.