Diabetic gastroparesis: what can complementary and alternative medicines do?
Diabetic gastroparesis: what can complementary and alternative medicines do?
复制标题
糖尿病胃轻瘫：补充和替代药物可以做什么？
DOI：
10.21037/lcm.2019.11.01
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发表时间：
2019-12
期刊：
影响因子：
--
通讯作者：
Ning Zhang
中科院分区：
文献类型：
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作者：
Shi-Yi Liu;Ying-Pan Zhao;Ning Zhang
糖尿病胃轻瘫(DGP)是长期存在的糖尿病(DM)的并发症，是一种慢性胃动力障碍。高达50%的1型和2型糖尿病患者有胃肠道症状，尤其是胃排空延迟(GE)。糖尿病几乎占所有胃瘫病例的三分之一。DGP最常见的症状包括餐后饱足、早饱、恶心、呕吐、腹胀和腹痛，这些症状明显导致生活质量下降。西医对DGP的治疗策略包括饮食调整、血糖控制、刺激胃运动的药物、止吐和促动力药物治疗以及非药物措施。然而，上述策略的有限有效性和副作用有时可能会受到应用的限制。补充和替代疗法如中药、针灸和推拿已被广泛使用了数千年，《DGP》上关于它们的研究越来越多，表明中医药在治疗顽固性恶心呕吐方面具有多方面的好处，还有助于缓解腹胀，副作用较少。在这里，我们重点介绍补充疗法和替代疗法的一般治疗策略，分别通过PubMed和CNKI在英文和中文出版物上发现。
Diabetic gastroparesis (DGP) is a complication of long-standing diabetes mellitus (DM) and a chronic motility disorder of the stomach. Up to 50% of patients with type 1 and 2 DM have the gastrointestinal manifestations, especially delayed gastric emptying (GE). And DM accounted for almost one-third of all cases of gastroparesis. The most common symptoms of DGP include postprandial fullness, early satiety, nausea, vomiting, bloating, and abdominal pain, which markedly lead to poor quality of life. Therapeutic strategies in western medicine for DGP involve dietary modification, the control of blood glucose, medications that stimulate gastric motor activity, anti-emetic and prokinetic drug therapy, and nonpharmacological measures. However, the limited effectiveness and the side effects of the strategies above mentioned may be restricted for their applications sometimes. Complementary and alternative therapy like Chinese herbs, acupuncture, moxibustion, and massage has been widely used for thousands of years and there are an increasing number of studies in DGP about them, suggesting that Chinese medicine could bring multiple benefits in the treatment of refractory nausea and vomiting and also help to alleviate abdominal distension with fewer side effects. Here, we focus on the general treatment strategies of complementary and alternative therapy, as discovered through PubMed and CNKI in English and Chinese publications, respectively.