Aureobasidins, new antifungal antibiotics. Taxonomy, fermentation, isolation, and properties.
Aureobasidins, new antifungal antibiotics. Taxonomy, fermentation, isolation, and properties.
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Aureobasidins，新型抗真菌抗生素。
DOI：
10.7164/antibiotics.44.919
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Hideyo Yamaguchi
中科院分区：
文献类型：
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作者：
K. Takesako;Katsushige Ikai;F. Haruna;Masahiro Endo;K. Shimanaka;E. Sono;Nakamura Teruya;Ikunoshin Kato;Hideyo Yamaguchi
从普鲁兰小孢子虫R106发酵液中分离到小孢子虫素A ~ R。Aureobasidins是一种环状沉积肽抗生素，其分子量范围为1.070 ~ 1148。aureobassidin对白色念珠菌具有较高的体外抗真菌活性。
Aureobasidins A to R were isolated from the fermentation broth of Aureobasidium pullulans R106. Aureobasidins are cyclic depsipeptide antibiotics with MW's ranging from 1.070 to 1,148. Aureobasidins showed high in vitro antifungal activity against Candida albicans.