Hospital-based surveillance for rotavirus diarrhea in children in Yangon, Myanmar
Hospital-based surveillance for rotavirus diarrhea in children in Yangon, Myanmar
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DOI：
10.1086/431509
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发表时间：
2005-09-01
影响因子：
6.4
通讯作者：
Htwe, TT
中科院分区：
文献类型：
--
作者：
Moe, K;Hummelman, EG;Htwe, TT
腹泻在缅甸是一种常见的儿童疾病，轮状病毒是腹泻的单一最重要的病原。2002年1月至2003年12月，在缅甸仰光的一家三级儿科医院对5岁以下儿童的轮状病毒腹泻进行了监测。使用酶联免疫吸附试验对因急性腹泻入院的儿童的粪便标本进行轮状病毒检测。在2年的研究期间（n = 30,869），腹泻是5671例（18%）5岁以下儿童住院的原因。在检测的1736份粪便标本中，有923份（53%）发现了轮状病毒，轮状病毒感染与大约10%的儿童住院有关。轮状病毒腹泻最常见于6 - 17个月大的儿童，在男孩中更为常见（62%的轮状病毒腹泻儿童为男孩）。轮状病毒病的季节性模式与各种原因引起的腹泻病的季节性模式相似，轮状病毒病的高峰期发生在11月至2月（即在凉爽干燥的季节）。在研究期间，53名因腹泻住院的儿童死亡。目前的研究证实了轮状病毒在儿童腹泻中的病因学作用的重要性。
Diarrhea is a common childhood illness in Myanmar, and rotavirus is the single most important etiological agent of diarrhea. Surveillance for rotavirus diarrhea in children < 5 years of age was conducted in a tertiary pediatric hospital in Yangon, Myanmar, from January 2002 through December 2003. Stool specimens obtained from children admitted to the hospital for acute diarrhea were tested for the presence of rotavirus by use of an enzyme-linked immunosorbent assay. Diarrhea was the cause of 5671 (18%) of all hospitalizations of children < 5 years of age during the 2-year study period (n = 30,869). Rotavirus was identified in 923 (53%) of the 1736 stool specimens tested, and rotavirus infection was associated with similar to 10% of all hospitalizations of children. Rotavirus diarrhea most frequently occurred in children 6 - 17 months of age, and it was more commonly identified in boys (62% of children with rotavirus diarrhea were boys). The seasonal pattern of rotavirus disease mimicked that of diarrheal illness due to all causes, with the peak season for rotavirus disease occurring from November through February (i.e., during the cool, dry season). During the study period, 53 of the children who were hospitalized for diarrhea died. The present study confirms the importance of the etiological role that rotavirus plays in childhood diarrhea.