Determination of optimal angles for variable nutation proton magnetic spin-lattice, T1, and spin-spin, T2, relaxation times measurement
Determination of optimal angles for variable nutation proton magnetic spin-lattice, T1, and spin-spin, T2, relaxation times measurement
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DOI：
10.1002/mrm.10661
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发表时间：
2004-01-01
影响因子：
3.3
通讯作者：
Rutt, BK
中科院分区：
文献类型：
--
作者：
Deoni, SCL;Peters, TM;Rutt, BK
结合多角度破坏梯度回忆回波（SPGR）和稳态自由进动（SSFP）成像，可以快速确定T-1和T-2。在此之前，我们演示了一种简单的方法来确定SPGR和SSFP角度集，该方法比均匀间隔的角度集提供更高的T-1和T-2精度。本文描述了一种更严格的确定角度的方法。在T-1和T-2估计中引入了加权最小二乘，并描述了一种新的加权函数。这种新方法适用于期望大T-1和T-2范围的成像应用，在大范围的T-1和T-2值范围内提供高而均匀的精度。(C) 2003 Wiley-Liss, Inc。
T-1 and T-2 can be rapidly determined with a combination of multiangle spoiled gradient recalled echo (SPGR) and steady-state free precession (SSFP) imaging. Previously, we demonstrated a simple method for determining the set of SPGR and SSFP angles that provided greater T-1 and T-2 precision than a set of uniformly spaced angles. In this article a more rigorous approach for determining angles is described. Weighted least-squares is also introduced for T-1 and T-2 estimation and a novel weighting function described. This new approach, suited for imaging applications where large T-1 and T-2 ranges are anticipated, provides high and uniform precision over a wide range of T-1 and T-2 values. (C) 2003 Wiley-Liss, Inc.