AhR-mediated potency of sediments and soils in estuarine and coastal areas of the Yellow Sea region: A comparison between Korea and China
AhR-mediated potency of sediments and soils in estuarine and coastal areas of the Yellow Sea region: A comparison between Korea and China
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DOI：
10.1016/j.envpol.2012.08.001
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发表时间：
2012-12-01
影响因子：
8.9
通讯作者：
Giesy, John R.
中科院分区：
文献类型：
--
作者：
Hong, Seongjin;Khim, Jong Seong;Giesy, John R.
使用 H4IIE-luc 反式激活生物测定法筛选从韩国和中国黄海沿岸收集的沉积物 (n = 45) 和土壤 (n = 37) 提取物在体外诱导二恶英类基因表达的能力。除了来自韩国的一些土壤外，观察到了显着的二恶英样效力。韩国和中国沉积物中 TCDD-EQ（2,3,7,8-四氯二苯并-对二恶英当量）的浓度相当，但土壤中 TCDD-EQ 的浓度是韩国的两倍。质量平衡分析表明，TCDD-EQ 的浓度在某种程度上依赖于化学和/或基质，但更具位点特异性。例如，可以识别的 TCDD-EQ 的比例因地点而异，这表明来源不同。在韩国样品中，未鉴定的 AhR 活性化合物在 TCDD-EQ 中所占比例较大，这表明韩国的来源比中国的来源更为复杂。通过考虑土地利用和当地活动，对 TCDD-EQ 的潜在来源进行了调查。 (C) 2012 Elsevier Ltd. 保留所有权利。
Extracts of sediments (n = 45) and soils (n = 37) collected from the coast of the Yellow Sea, in Korea and China, were screened for their ability to induce dioxin-like gene expression in vitro using the H4IIE-luc, transactivation bioassay. Significant dioxin-like potency was observed except for a few soils from Korea. Concentrations of TCDD-EQ (2,3,7,8-tetrachlorodibenzo-p-dioxin equivalents) in sediments were comparable between Korea and China, but concentrations of TCDD-EQ in soil were 2-fold greater from Korea. Mass balance analysis indicated that concentrations of TCDD-EQ were to some degree chemical- and/or matrix-dependent, but were much more site-specific. For example, the proportion of the TCDD-EQ that could be identified varied among locations, which suggests different sources. Unidentified AhR-active compounds represented a greater proportion of the TCDD-EQ in samples from Korea, which suggests that sources in Korea were more complex than those in China. Potential sources of TCDD-EQ were investigated by considering land-uses and local activities. (C) 2012 Elsevier Ltd. All rights reserved.