Regioselective Bromocyclization of Unsaturated N-Tosylcarbamates Promoted by N,N-Dibromosulfonamides
Regioselective Bromocyclization of Unsaturated N-Tosylcarbamates Promoted by N,N-Dibromosulfonamides
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N,N-二溴磺酰胺促进不饱和 N-甲苯磺酰氨基甲酸酯的区域选择性溴环化
DOI：
10.1055/s-0034-1378314
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发表时间：
2014-08-01
期刊：
影响因子：
2
通讯作者：
Zhou, Ling
中科院分区：
文献类型：
--
作者：
Fan, Guo-Tao;Sun, Ming-Hui;Zhou, Ling
摘要发展了不饱和N-对甲苯磺酰基氨基甲酸酯的简单、高区域选择性的溴-N-环化和溴-O-环化反应。N，N-二溴磺酰胺作为溴化试剂在这些亲电环化反应中起着重要的作用。这种方法在有机合成中很有用。所需产物可以顺利地转化为氮丙啶或环氧化物。
Abstract Simple and highly regioselective bromo-N-cyclization and bromo-O-cyclization reactions of unsaturated N-tosylcarbamates have been developed. The use of N,N-dibromosulfonamides as brominating reagents plays an important role in these electrophilic cyclization reactions. This method is useful in organic synthesis. The desired products can be smoothly transformed into aziridines or epoxides.