Domino paired kidney donation: a strategy to make best use of live non-directed donation
Domino paired kidney donation: a strategy to make best use of live non-directed donation
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DOI：
10.1016/s0140-6736(06)69115-0
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发表时间：
2006-07-01
期刊：
影响因子：
168.9
通讯作者：
Segev, Dorry L.
中科院分区：
文献类型：
--
作者：
Montgomery, Robert A.;Gentry, Sommer E.;Segev, Dorry L.
活体非定向（LND）捐赠者，也称为利他主义者，好撒玛利亚人，匿名或慈善社区捐赠者，是一种新的快速增长的实体器官移植来源。1-6个人自愿捐献器官而没有指定的受体是出乎意料的，但可能是社会对器官可用性日益严重的危机的反应。在这种短缺的背景下，卫生专业人员试图充分利用LND供体的肾脏。我们提出了一种新的配对捐赠的应用，有可能成倍增加谁可以从每个LND捐赠受益的收件人的数量。目前，没有普遍接受的系统分配LND捐赠者的器官。受者的选择由移植中心决定，LND捐赠者已经提交，并且通常由三种模式之一指导：以捐赠者为中心，以捐赠者为中心或以社会为中心的分配。7这些模式都得到了有效的道德规范的支持。
Living non-directed (LND) donors, also known as altruistic, good Samaritan, anonymous, or benevolent community donors, are a new and rapidly growing source of solid organs for transplantation. 1–6 The willingness of individuals to donate organs without a designated recipient has been unexpected, but has probably developed as a societal response to the growing crisis in organ availability. In the context of this shortage, health professionals have attempted to make the best use of kidneys from LND donors. We present a novel application of paired donation that has the potential to multiply the number of recipients who can benefit from each LND donation.At present, there is no universally accepted system for allocation of organs from LND donors. Selection of recipients has been at the discretion of the transplant centres where LND donors have presented and has generally been guided by one of three models: donorcentric, recipient-centric, or sociocentric allocation. 7 Each of these models is supported by valid ethical