A STUDY ON THE INTERSTITIAL CELLS OF THE HUMAN TESTIS, ESPECIALLY ON THEIR FINE‐STRUCTURAL PATHOLOGY †
A STUDY ON THE INTERSTITIAL CELLS OF THE HUMAN TESTIS, ESPECIALLY ON THEIR FINE‐STRUCTURAL PATHOLOGY †
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对人类睾丸间质细胞的研究，特别是对其精细结构病理学的研究 †
DOI：
10.1111/j.1440-1827.1965.tb00003.x
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发表时间：
1965
影响因子：
2.2
通讯作者：
S. Hatakeyama
中科院分区：
文献类型：
--
作者：
S. Hatakeyama
布因和ANCEL（1904）首先提出细胞的激素活性，目前认为睾丸间质细胞和肾上腺皮质是身体的两个主要雄激素来源。尽管STIEVE（1930）、MUSSE EN（1932）和SNIFPEN（1950）在光-光水平上详细描述了它们的细胞形态学，但直到最近才尝试用电子显微镜和细胞化学方法对其激素分泌进行动态形态学分析。对人、大鼠、家兔和负鼠睾丸间质细胞的超微结构进行了研究。然而，对不同内分泌状态下人体细胞的精细结构研究至今未见报道。为了了解细胞学的变化，在整个功能的改变，作者检查了人类活检材料从一系列代表不同年龄和疾病的激素和临床结果。
BOUIN and ANCEL (1904) were the first to suggest hormonal activity of the cells and at present time it is believed that both the testicular interstitial cells and the adrenal cortex are two major androgen sources of the body. Although their cytomorphology at light-optical level has been described in detail by STIEVE (1930), MUSSE EN (1932) and SNIFPEN (1950), a dynamic morphological analysis of their hormon secretion has been only lately attempted by means of electron microscopy and cytochemistry. There have been several investigations on the ultrastructure of the testicular interstitial cells of man, rat, rabbit and opossum. However, a fine structural study of the cells in human beings under various endocrinological status has not been reported until now. In order to understand the cytological changes in response to functional alteration on the whole, the author examined human biopsy materials from a series representing varying ages and diseases referring to the hormonal and clinical findings.