Self-Deferral, HIV Infection, and the Blood Supply
Self-Deferral, HIV Infection, and the Blood Supply
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自我延期、艾滋病毒感染和血液供应
DOI：
10.1177/0193841x9001400609
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发表时间：
1990
影响因子：
0.9
通讯作者：
A. Novick
中科院分区：
文献类型：
--
作者：
E. H. Kaplan;A. Novick
这篇文章评估了自我延迟的有效性，这是一种在捐献血液的实验室检测出现之前，为保护美国血液供应免受艾滋病毒感染而实施的社交屏蔽。在简要讨论了该计划的历史之后，开发了数学模型来估计在自我延迟之前发生的最终导致艾滋病的感染性输血的数量。分析表明，在从实施自我推迟到开始实验室筛查的两年期间，可以预防的艾滋病指示的最大感染输血数量中，有相当大比例得到了避免。
This article evaluates the effectiveness of self-deferral, a social screen implemented to protect the U.S. blood supply from HIV infection prior to the advent of laboratory testing of donated blood. Following a brief discussion of the history of this program, mathematical models are developed to estimate the number of infectious transfusions ultimately leading to AIDS that occurred prior to self-deferral. The analysis suggests that a significant percentage of the maximum number of AIDS-indicated infectious transfusions preventable were averted during the 2 years from implementation of self-deferral to the start of laboratory screening.