Toxoplasma gondii and Cryptosporidium parvum lack detectable DNA cytosine methylation
Toxoplasma gondii and Cryptosporidium parvum lack detectable DNA cytosine methylation
复制标题
DOI:
10.1128/ec.00448-07
复制
发表时间:
2008-03-01
期刊:
影响因子:
--
通讯作者:
Kim, Kami
中科院分区:
文献类型:
--
作者:
Gissot, Mathieu;Choi, Sang-Woon;Kim, Kami
Epigenetic factors play a role in the expression of virulence traits in Apicomplexa. Apicomplexan genomes encode putative DNA cytosine methylation enzymes. To assess the presence of cytosine methylation of Toxoplasma gondii and Cryptosporidium parvum DNA, we used mass spectrometry analysis and confirmed that these organisms lack detectable methylcytosine in their DNA.