A Versatile Total Synthesis of 8-Oxyberberine and Oxohomoberberines
A Versatile Total Synthesis of 8-Oxyberberine and Oxohomoberberines
复制标题
8-氧化小檗碱和氧化高小檗碱的多功能全合成
DOI：
10.1002/cjoc.201400612
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Yong Wu
中科院分区：
文献类型：
--
作者：
Yun He;Yang Zheng;Li Hai;Yong Wu
The total syntheses of 8‐oxyberberine and oxohomoberberines were accomplished starting from commercially available 5‐bromobenzo[d][1,3]dioxole, piperonal and sesamol in high total yield. The key steps involved a modified Pomeranz‐Fritsch reaction and the intramolecular Heck cyclization. This approach is short, convenient and suitable for the preparation of homoberberine analogues.
