Applications of hyperpolarized helium-3 gas magnetic resonance imaging in pediatric lung disease.
Applications of hyperpolarized helium-3 gas magnetic resonance imaging in pediatric lung disease.
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DOI：
10.1097/00002142-200306000-00003
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发表时间：
2003-06-01
期刊：
影响因子：
--
通讯作者：
de Lange, Eduard E
中科院分区：
文献类型：
--
作者：
Altes, Talissa A;de Lange, Eduard E
肺的超极化气体磁共振成像（MRI）提供了肺空气空间的高时间和空间分辨率图像，可用于阐明肺通气和形态学。由于不涉及电离辐射，超极化气体MRI是评估儿童肺部疾病的理想选择。在本文中，我们简要介绍了超极化气体MRI的基本原理，回顾了超极化气体MRI在两种儿科肺部疾病（哮喘和囊性纤维化）中的文献，并讨论了超极化气体成像在儿科肺部疾病中的临床应用前景。
Hyperpolarized gas magnetic resonance imaging (MRI) of the lung provides high temporal and spatial resolution images of the air spaces of the lung and can be used to elucidate both lung ventilation and morphology. Because no ionizing radiation is involved, hyperpolarized gas MRI is ideal for the evaluation of pediatric lung diseases. In the article, we describe briefly the basic principles of hyperpolarized gas MRI, review the literature of hyperpolarized gas MRI in two pediatric lung diseases (asthma and cystic fibrosis), and discuss possible future clinical applications of hyperpolarized gas imaging in pediatric lung disease.