増大特集 記憶と忘却に関わる脳のしくみ-分子機構から健忘の症候まで 社会的文脈における記憶と内側前頭前皮質の役割
増大特集 記憶と忘却に関わる脳のしくみ-分子機構から健忘の症候まで 社会的文脈における記憶と内側前頭前皮質の役割
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专题：参与记忆和遗忘的大脑机制——从分子机制到健忘症症状社会背景下的记忆以及内侧前额叶皮层的作用
DOI：
10.11477/mf.1416201076
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发表时间：
2018
期刊：
影响因子：
--
通讯作者：
月浦 崇
中科院分区：
文献类型：
--
作者：
杉本 光;月浦 崇
社会记忆是一种在社会背景的多个领域的情景记忆。功能神经影像学研究表明，内侧前额叶皮层（mPFC）在社会记忆中起着重要作用。然而，很少有人知道mPFC内的社会记忆中的可分离的角色。本文的目的是总结功能性神经影像学研究调查社会记忆，并提出一个假设模型的mPFC子区域的社会记忆的贡献。在本文中，我们将mPFC分为三个亚区的眶，腹，背区。功能神经影像学研究表明，眼眶mPFC（眶额皮质）有助于情景记忆中的奖励过程，并且在初级、次级和社会奖励中发现了与奖励相关的激活。腹侧前额叶皮层在自我参照加工中的作用已经被发现，该加工的编码操作产生了情景记忆中的自我参照效应。背侧mPFC的激活在高要求的过程中被观察到，包括认知控制和社会认知，如在情景编码和提取过程中对他人的印象形成。mPFC三个亚区内部以及mPFC与内侧颞叶之间的相互作用机制可能对社会记忆产生影响。
Social memory is a form of episodic memories in multiple domains of social context. Functional neuroimaging studies have demonstrated that the medial prefrontal cortex (mPFC) plays an important role in social memories. However, little is known about the dissociable roles within mPFC in social memories. The purpose of this article was to summarize functional neuroimaging studies investigating social memories, and to propose a hypothetical model regarding the contribution of mPFC sub-regions to social memories. In this article, we divided mPFC into three sub-regions of the orbital, ventral, and dorsal regions. Functional neuroimaging studies have shown that the orbital mPFC (orbitofrontal cortex) contributes to the reward process in episodic memory, and that the reward-related activation is identified in primary, secondary, and social rewards. A role of the ventral mPFC has been found in the self-referential process, and the encoding operation of this process produces the self-reference effect in episodic memory. Activation in the dorsal mPFC has been observed in high demanding processes including cognitive control and in social cognition such as impression formation for others during episodic encoding and retrieval. The interactive mechanisms within three sub-regions of mPFC and between mPFC and the medial temporal lobe could contribute to social memories.