INTEGRITY OF FOVEAL PHOTORECEPTOR LAYER IN CENTRAL RETINAL VEIN OCCLUSION
INTEGRITY OF FOVEAL PHOTORECEPTOR LAYER IN CENTRAL RETINAL VEIN OCCLUSION
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DOI：
10.1097/iae.0b013e3181840b3c
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发表时间：
2008-11-01
影响因子：
3.3
通讯作者：
Yoshimura, Nagahisa
中科院分区：
文献类型：
--
作者：
Ota, Masafumi;Tsujikawa, Akitaka;Yoshimura, Nagahisa
目的：目的：探讨视网膜中央静脉阻塞（CRVO）黄斑水肿（ME）消退后的最终视力与黄斑中心凹感光层完整性的相关性。在光学相干断层扫描，中央凹感光层的完整性进行了研究，使用的感光（IS/OS）线的内部和外部段之间的交界处作为hallmark.Results：在最后一次访问，中央凹厚度下降到生理水平在所有的眼睛。光学相干断层扫描（OCT）显示14眼中心凹IS/OS线，13眼无IS/OS线。与ME消退一致，末次访视时视力显著改善。无IS/OS线者的最终视力明显低于有IS/OS线者（P < 0.0001）。此外，视网膜中央静脉阻塞视网膜中央凹光感受器层的完整性与初始视网膜灌注状态（P = 0.0156）和初始视力（P = 0.0050）显著相关。结论：视网膜中央静脉阻塞视网膜中央凹光感受器层的完整性与视网膜中央凹光感受器层的完整性密切相关。
Purpose: To study the correlation between final visual acuity and integrity of the foveal photoreceptor layer after resolution of macular edema (ME) associated with central retinal vein occlusion (CRVO).Methods: We studied retrospectively 27 eyes of 27 patients with resolved ME associated with central retinal vein occlusion. On optical coherence tomography, integrity of the foveal photoreceptor layer was studied using the junctions between inner and outer segments of the photoreceptor (IS/OS) line as a hallmark.Results: At the final visit, foveal thickness was decreased to a physiologic level in all eyes. On optical coherence tomography, 14 eyes showed the IS/OS line in the fovea, whereas 13 eyes showed no IS/OS line. In concordance with resolution of the ME, visual acuity had improved significantly by the final visit. However, final visual acuity in eyes without an IS/OS line was significantly poorer than that in eyes with an IS/OS line (P < 0.0001). In addition, integrity of the foveal photoreceptor layer after resolution of the ME had a significant correlation with the initial retinal perfusion status (P = 0.0156) and with initial visual acuity (P = 0.0050).Conclusions: After resolution of the ME associated with central retinal vein occlusion, visual acuity is closely associated with integrity of the foveal photoreceptor layer.