Neuroradiographic, endocrinologic, and ophthalmic correlates of adverse developmental outcomes in children with optic nerve hypoplasia: A prospective study
Neuroradiographic, endocrinologic, and ophthalmic correlates of adverse developmental outcomes in children with optic nerve hypoplasia: A prospective study
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DOI：
10.1542/peds.2007-1825
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发表时间：
2008-03-01
期刊：
影响因子：
8
通讯作者：
Borchert, Mark
中科院分区：
文献类型：
--
作者：
Garcia-Filion, Pamela;Epport, Karen;Borchert, Mark
背景据报道，视神经发育不全会导致发育迟缓，这是儿童失明的主要原因，但尚未对其患病率及其与视神经发育不全相关病理的相关性进行系统研究。OBJECTIVE.本研究的目的是确定视神经发育不良儿童的发育结果以及其发育与神经放射学、内分泌学和眼科检查结果的相关性。我们对73名被诊断为视神经发育不全的受试者进行了前瞻性分析，
BACKGROUND. Developmental delay has been reported to occur with optic nerve hypoplasia, a leading cause of pediatric blindness, but has not been systematically examined for its prevalence and correlation with associated pathologies of optic nerve hypoplasia. OBJECTIVE. The purpose of this study was to determine the developmental outcomes of children with optic nerve hypoplasia and the correlation of development with neuroradiographic, endocrinologic, and ophthalmic findings.METHODS. We conducted a prospective analysis of 73 subjects diagnosed with optic nerve hypoplasia at