Grapheme-color and tone-color synesthesia is associated with structural brain changes in visual regions implicated in color, form, and motion
Grapheme-color and tone-color synesthesia is associated with structural brain changes in visual regions implicated in color, form, and motion
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DOI：
10.1080/17588928.2011.594499
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发表时间：
2012-01-01
影响因子：
2
通讯作者：
Kanai, Ryota
中科院分区：
文献类型：
--
作者：
Banissy, Michael J.;Stewart, Lauren;Kanai, Ryota
联觉是一种罕见的情况，其中一种感觉方式的刺激会导致另一种感觉方式的次要体验。不同的说法将这种情况归因于联觉者和非联觉者之间的神经解剖学差异或感觉脑区域如何相互作用的功能差异。这项研究采用基于体素的形态测量来检查同时经历字素颜色和音调颜色联觉作为诱发感觉的联觉者与非联觉者相比是否表现出灰质体积的神经解剖学差异。我们观察到联觉者显示左梭状后回 (FG) 灰质体积增加，但左 FG 和左 MT/V5 前部区域随之减少。这些发现意味着颜色联觉与视觉系统相邻区域之间的神经解剖学变化有关。
Synesthesia is a rare condition in which stimulation in one modality leads to a secondary experience in another sensory modality. Varying accounts attribute the condition to either neuroanatomical differences between the synesthetes and non-synesthetes or functional differences in how sensory brain regions interact. This study employed voxel-based morphometry to examine whether synesthetes who experience both grapheme-color and tone-color synesthesia as their evoked sensation show neuroanatomical differences in gray matter volume compared to non-synesthetes. We observed that synesthetes showed an increase in gray matter volume in left posterior fusiform gyrus (FG), but a concomitant decrease in anterior regions of left FG and left MT/V5. These findings imply that synesthesia for color is linked to neuroanatomical changes between adjacent regions of the visual system.