Influenza Virus Aerosols in Human Exhaled Breath: Particle Size, Culturability, and Effect of Surgical Masks

Influenza Virus Aerosols in Human Exhaled Breath: Particle Size, Culturability, and Effect of Surgical Masks
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DOI:
10.1371/journal.ppat.1003205
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发表时间:
2013-03-01
期刊:
影响因子:
6.7
通讯作者:
McDevitt, James J.
McDevitt, James J.
中科院分区:
医学1区
文献类型:
--
作者:
Milton, Donald K.;Fabian, M. Patricia;McDevitt, James J.

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美国疾病控制与预防中心(CDC)建议医疗机构为流感患者提供口罩,以此作为减少传染给医护人员和其他患者的一种手段,并且最近的一份报告表明,医用外科口罩能够捕捉大飞沫喷雾中的流感病毒。然而,关于流感病毒气溶胶排放、呼出的气溶胶的传染性的数据极少,而且关于口罩对季节性流感患者的病毒气溶胶排放的影响没有相关数据。我们收集了呼出颗粒的样本(一次戴口罩,一次不戴口罩),分为两种粒径范围(“粗颗粒”>5微米,“细颗粒”
The CDC recommends that healthcare settings provide influenza patients with facemasks as a means of reducing transmission to staff and other patients, and a recent report suggested that surgical masks can capture influenza virus in large droplet spray. However, there is minimal data on influenza virus aerosol shedding, the infectiousness of exhaled aerosols, and none on the impact of facemasks on viral aerosol shedding from patients with seasonal influenza. We collected samples of exhaled particles (one with and one without a facemask) in two size fractions ("coarse">5 mu m, "fine"