Automated counting of nucleated red blood cells in blood samples of newborns

Automated counting of nucleated red blood cells in blood samples of newborns
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DOI:
10.1046/j.1365-2257.2002.00477.x
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发表时间:
2002-12-01
期刊:
CLINICAL AND LABORATORY HAEMATOLOGY
影响因子:
--
通讯作者:
van der Meer, W
van der Meer, W
中科院分区:
其他
文献类型:
--
作者:
de Keijzer, MH;van der Meer, W

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血液样本中的有核红细胞 (NRBC) 会干扰多种类型的自动血液分析仪上的白细胞 (WBC) 计数。这使得有必要通过显微镜计数 NRBC 来校正 WBC 计数。本报告描述了对两种分析仪(Cell-Dyn 4000 和 Sysmex XE-2100)的评估,这两种分析仪使用新技术来识别和计数 NRBC。我们得出的结论是,在 NRBC 存在的情况下,Cell-Dyn 4000 和 Sysmex XE-2100 都能提供准确的 WBC 计数。此外,与显微镜观察相比,他们可以正确计数 NRBC。
Nucleated red blood cells (NRBC) in blood samples interfere with the white blood cell (WBC) count on many types of automated haematology analysers. This makes it necessary to correct the WBC count by counting NRBC microscopically. This report describes the evaluation of two analysers, the Cell-Dyn 4000 and the Sysmex XE-2100, which use new techniques to recognize and enumerate NRBC. We conclude that both the Cell-Dyn 4000 and the Sysmex XE-2100 give an accurate WBC count in the presence of NRBC. Furthermore, they can enumerate NRBC correctly when compared with microscopic observation.