The power of personality in discriminating between healthy aging and early-stage Alzheimer's disease
The power of personality in discriminating between healthy aging and early-stage Alzheimer's disease
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DOI：
10.1093/geronb/62.6.p353
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发表时间：
2007-11-01
影响因子：
6.2
通讯作者：
Larsen, Randy
中科院分区：
文献类型：
--
作者：
Duchek, Janet M.;Balota, David A.;Larsen, Randy
这项研究考察了阿尔茨海默型痴呆症(DAT)早期阶段的人格差异与健康老龄化的关系，以及人格在区分健康老龄化和早期DAT方面的能力。对四组参与者(中年对照组、老年对照组、非常轻微的DAT患者和轻度DAT患者)及其家人进行了Costa和McCrae的NEO五因素问卷调查。根据自我报告和告密者报告，与没有DAT的健康人相比，患有非常轻微DAT的人神经质增加，责任心下降；与患有非常轻微DAT的人相比，患有轻度DAT的人神经质增加，责任心降低。此外，告密者报告的神经质和尽职尽责在区分健康衰老和非常轻微的DAT方面捕捉到了显著的独特差异，超过了标准的神经心理学测试。讨论的重点是人格特征作为早期DAT的非认知指标的重要性。
This study examined differences in personality in the earliest stages of dementia of the Alzheimer type (DAT) relative to healthy aging, and the power of personality in discriminating healthy aging from early-stage DAT. Four groups of participants (middle-aged controls, older controls, persons with very mild DAT, and persons with mild DAT) and their families were administered Costa and McCrae's NEO Five-Factor Inventory. On the basis of both self-report and informant report, there was an increase in neuroticism and a decrease in conscientiousness in persons with very mild DAT relative to healthy individuals without it, and in persons with mild DAT relative to those with very mild DAT. Moreover, informant reports of neuroticism and conscientiousness capture substantial unique variance in discriminating healthy aging and very mild DAT, above and beyond standard neuropsychological tests. Discussion focuses on the importance of personality traits as a noncognitive indicator of early-stage DAT.