Transverse elasticity of rabbit sciatic nerves tested by in vitro compression
Transverse elasticity of rabbit sciatic nerves tested by in vitro compression
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DOI：
10.1080/02533839.2004.9670951
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发表时间：
2004-11-01
影响因子：
1.1
通讯作者：
Lin, CW
中科院分区：
文献类型：
--
作者：
Ju, MS;Lin, CCK;Lin, CW
对兔坐骨神经在体外逐步线性压缩试验下的杨氏模量进行了估计。采用特制的平行压迫装置在横向压迫兔坐骨神经节段。使用安装在显微镜上的相机同时拍摄了横切面的数字图像。测量了压缩装置的受力和平行板间的间隙。利用数字化的神经横切面图像构建神经二维模型。平行压缩结果显示，兔坐骨神经杨氏模量平均值为41.6±5.0 kPa。通过直接目测和有限元模型仿真结果与实验数据的对比，我们可以认为大筋膜束是主要的承重构件，而小筋膜束和神经外膜等疏松结缔组织在平行压缩过程中承受的载荷较小。
The Young's modulus of a rabbit sciatic nerve under stepwise in vitro linear compression test was estimated. Segments of rabbit sciatic nerves were compressed in the transverse direction with a custom-made parallel compression apparatus. Digital images of the cross-sectional face were taken simultaneously by using a camera mounted on a microscope. The applied force and the gap between the parallel plates of the compression apparatus were measured. Digitized images of the nerve cross-sections were used to construct two-dimensional models of the nerves. The parallel compression results showed that the mean Young's modulus of rabbit sciatic nerves was 41.6+/-5.0 kPa. By direct visual inspection and by comparing the finite element model simulation results and experimental data, we may suggest that the large fascicle is the main load-bearing component while the small fascicle and the loose connective tissues like the epineurium bear less load in the parallel compression process.