Cognitive control in the posterior frontolateral cortex: evidence from common activations in task coordination, interference control, and working memory
Cognitive control in the posterior frontolateral cortex: evidence from common activations in task coordination, interference control, and working memory
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DOI：
10.1016/j.neuroimage.2004.06.007
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发表时间：
2004-10-01
期刊：
影响因子：
5.7
通讯作者：
von Cramon, DY
中科院分区：
文献类型：
--
作者：
Derrfuss, J;Brass, M;von Cramon, DY
认知控制通常与中背外侧前额叶皮层的激活有关。然而，最近的证据强调了额下沟和中央前沟交界处周围更靠后的额外侧区域（额下交界区，IFJ）的重要性。在本实验中，我们研究了 IFJ 在任务切换范式、手动 Stroop 任务和会话内组内设计中的言语 n-back 任务中的参与情况。在计算各个任务的对比后，将生成的 z 图叠加起来，以识别这些任务通常激活的区域。常见的激活存在于 IFJ、延伸至 BA 8 内侧的前 SMA、与额下沟接壤的额中回、前岛叶以及顶叶和丘脑区域。这些结果表明，存在一个由前额叶、顶叶和皮层下区域组成的网络，介导任务协调、干扰控制和工作记忆中的认知控制。特别是，这些结果为以下假设提供了证据：在额外侧皮层中，不仅是中背外侧区域，而且 IFJ 在认知控制中也发挥着重要作用。 (C) 2004 Elsevier Inc. 保留所有权利。
Cognitive control has often been associated with activations of middorsolateral prefrontal cortex. However, recent evidence highlights the importance of a more posterior frontolateral region around the junction of the inferior frontal sulcus and the inferior precentral sulcus (the inferior frontal junction area, IFJ). In the present experiment, we investigated the involvement of the IFJ in a task-switching paradigm, a manual Stroop task, and a verbal n-back task in a within-session within-group design. After computing contrasts for the individual tasks, the resulting z maps were overlaid to identify areas commonly activated by these tasks. Common activations were found in the IFJ, in the pre-SMA extending into mesial BA 8, in the middle frontal gyrus bordering the inferior frontal sulcus, in the anterior insula, and in parietal and thalamic regions. These results indicate the existence of a network of prefrontal, parietal, and subcortical regions mediating cognitive control in task coordination, interference control, and working memory. In particular, the results provide evidence for the assumption that, in the frontolateral cortex, not only the middorsolateral region but also the IFJ plays an important role in cognitive control. (C) 2004 Elsevier Inc. All rights reserved.