Alcohol, drug intoxication, or both at the time of burn injury as a predictor of complications and mortality in hospitalized patients with burns
Alcohol, drug intoxication, or both at the time of burn injury as a predictor of complications and mortality in hospitalized patients with burns
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DOI：
10.1097/00004630-199611000-00010
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发表时间：
1996-01-01
期刊：
影响因子：
--
通讯作者：
Hunt, J. L.
中科院分区：
文献类型：
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作者：
Grobmyer, S. R.;Maniscalco, S. P.;Hunt, J. L.
本研究的目的是描述烧伤住院患者受伤时药物和酒精中毒与随后的并发症和死亡率之间的关系。一个计算机化的烧伤数据库被用来分析数据的3047连续成人（21至75岁）住院患者的烧伤承认1982年1月至1994年8月之间。数据中毒（历史，血液酒精含量，或积极的药物筛选）和非中毒患者进行了比较。同样的分析也对同一时期收治的429例连续青少年烧伤患者（年龄14至20岁）进行了分析。烧伤时中毒发生率为6.9%。在年龄、性别、种族或烧伤面积方面没有显著差异。中毒患者有较高的发生率的相关伤害。皮肤移植物丢失、蜂窝织炎、供皮区转换、低血压和肺炎在中毒组中更常见。他们也有更多的重症监护室入院，呼吸机日，手术，输血和总住院日。中毒患者的死亡率（7.1%）低于对照组（10.9%）。烧伤时的中毒是成年烧伤患者并发症的重要预测因素。
The objective of this study was to characterize the association between drug and alcohol intoxication at the time of injury and subsequent complications and mortality in hospitalized patients with burns. A computerized burn database was used to analyze data on 3047 consecutive adult (21 to 75 years) hospitalized patients with burns admitted between January 1982 and August 1994. Data for intoxicated (by history, blood alcohol content, or positive drug screen) and nonintoxicated patients were compared. The same analysis was also conducted on 429 consecutive adolescent patients with burns (ages 14 to 20 years) admitted during the same time period. The incidence of intoxication at the time of burn was 6.9%. No significant differences in age, sex, race, or burn size were noted. Intoxicated patients had a higher incidence of associated injuries. Skin graft loss, cellulitis, donor site conversion, hypotension, and pneumonia were more common in the intoxicated group. They also had more intensive care unit admissions, ventilator days, operations, transfusions, and total hospital days. Intoxicated patients had a lower mortality (7.1%) than patients in the control group (10.9%). Intoxication at the time of burn injury is an important predictor of complications in adult patients with burns.